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Vivo Case Studies
By Aubrey Organics

Beta Vulgaris (Beetroot) Extract   

Beets are known for their incredible anti-oxidant power and rich nutrient value. They are a common ingredient in many cleansing regimens, because they provide so many different benefits for the human body. They grow all across the Americas and Europe, and are mainly harvested for the plump "beetroot" that grows underground.

Aubrey® use beetroot extract in their Revitalizing, Age-Defying, Calming and Clarifying toners, because it provides a clean, nutritious moisture for the skin. In clinical tests performed independently of Aubrey Organics, Inc., beetroot was proven to increase the skin's moisture for up to 8 hours after application (see study below)

Beetroot in Vivo Study

4 volunteers, age 23-36, were given a single application of 1% beetroot extract in a test cream.

After application, their skin was measured every two hours by corneometer, and was found to hold an increased hydration level for over 8 hours.


Aubrey® strive to produce only the purest and most effective personal care products, always made with 100% natural ingredients. their toners are not made to dry out or deplete the skin, but rather to re-introduce clean moisture for all skin types. Each of their toners is formulated for different skin- Revitalizing for dry skin, Age Defying for all skin types, Calming for sensitive skin and Clarifying for oily or acne prone skin. Each formulation will combat the particular concern for that skin type, while balancing and toning to leave skin clean and lightly hydrated. For more information on natural Aubrey® ingredients, take a look at our INCI Dictionary

Aster Tripolium (Sea Aster) Extract   

Sea Aster is found in salty waters along the shoreline of Northern Europe, and is very resistant to salt, wind and waves. Even though the flowers look delicate, the plant is often found in the areas of the shore where the harshest waves hit. Built for resiliency, it is filled with strengthening nutrients.

Sea Aster extract naturally combats redness and sensitivity. Moreover, the rich nutrients in Sea Aster extract promote hydrated, healthy skin. Aubrey® uses Sea Aster extract in EVERY one of our Calming Skin Therapy products.

The whole line of products is based around this particular ingredient for one reason: it is extremely effective. Sensitive skin can react adversely to many petrochemicals that may not bother other skin types, so shopping naturally is particularly beneficial for those with these sensitivities. As shown in clinical studies performed independently of Aubrey Organics, Inc., Sea Aster extract proved to be a highly effective natural ingredient.

Sea Aster Extract in Vivo Study  (Studied on Real Human Volunteers)

20 volunteers (both male and female) from age 30 to 65 applied Sea Aster extract in a test cream twice daily for 28 days. Every volunteer had a history of some type of skin redness, whether permanent or transitory. At the end of 28 days, they participated in a self-evaluation test to measure the results. This is what they reported:
  • 80% of the volunteers perceived an improvement of the skin quality
  • 90% of the volunteers perceived smoother skin
  • 80% of the volunteers perceived an improvement of the skin firmness
  • 100% of volunteers perceived an improvement of the hydration level
  • 75% would buy the product

*Permission to use study and photographs given to Aubrey Organics, Inc. May not be used or distributed without written consent of Biotech Marine.

Carnosine, Milk Thistle and Vitamin E   

Clinical tests demonstrate topical application of carnosine (an amino acid) and vitamin E, two powerful antioxidants, plus milk thistle extract, a detoxifier, resulted in increased firmness and hydration, and advanced anti-wrinkle and anti-glycation activity on the skin.

Glycation happens when sugar molecules bind to collagen and elastin proteins in the skin to form damaging free radicals (not unlike the free radicals caused by too much sun). Free radicals are a primary cause of aging. They lead to inflammation, which in turn breaks down the skin's connective tissue, resulting in wrinkles, yellowing of the skin, loss of elasticity due to a hardening of collagen and elastin fibers in the dermis, and other visible signs of aging.

Studies conducted over 28 days show a synergistic blend of these three ingredients in a liposome delivery system helps stop glycation by preventing glucose/collagen bonds from forming and breaking down free radicals already present in the skin.

Rejuvenating Properties of Carnosine, Milk Thistle & Vitamin E



This study involved 20 women ages 38 to 65. A test cream containing a liposome preparation of 2% carnosine, milk thistle and vitamin E was applied to the inner forearm of the subjects twice a day for 28 days.
Biomechanical properties of the skin were then evaluated by determining the skin's firmness, hydration and smoothness. Results showed this preparation improved all parameters in all subjects after 28 days of treatment when compared to untreated skin.



A test cream containing a liposome preparation of 2% carnosine, milk thistle and vitamin E was applied twice daily for 28 days to the crow's feet and foreheads of 20 women ages 38 to 65.
Wrinkle depth was evaluated after 14 days of treatment and again after 28 days. Results showed that at the 14 day mark, the depth of wrinkles was somewhat diminished. After 28 days of treatment, depth of wrinkles had been reduced by 27% in the crow's feet area, and by 24% on the forehead

*Permission to use study and photographs given to Aubrey Organics, Inc. May not be used or distributed without written consent of Mibelle©.

Glacier Water Liposomes   

Glacier water liposomes contained in our two Sparkling Glacier Complexion Mists are formulated with Swiss glacier water from one of the highest sources of mineral water in Europe, guaranteeing its purity and freshness. This glacier water is encapsulated into liposomes, which deliver moisture onto the skin in a time-release fashion, resulting in deep and long-lasting hydration

In Vivo Hydration Study*

Results showed glacier water liposomes significantly increased and maintained skin hydration when compared to the placebo:
  • 8 hours after application, the skin's moisture content remained at more than 22.9% with a 5% glacier water application, compared to only 9.9% with the placebo.

  • 24 hours after application, hydration with the 5% glacier water liposomes gel remained at 10.3% compared to only 1.2% with placebo

*Permission to use study and photographs given to Aubrey Organics, Inc. May not be used or distributed without written consent of Mibelle.

Laminaria Ochroleuca (Golden Seaweed) Extract   

Aubrey® have always been committed to finding natural solutions to any personal care problem. Aubrey® was the first to ever use Laminaria Ochroleuca, also known as "golden seaweed," in skin care products.

Golden seaweed naturally defends the skin from daily stressors. Found along the coasts of Ireland and Great Britain, it holds onto rocks in tidal areas, and is most notable for its beautiful yellow-gold fronds. Because it is found in shallow water, it is often exposed to harsh sunlight, and has developed its own protective mechanism to combat the effects of UVA and UVB rays. Rich in nutrients, this extract helps smooth and hydrate the skin.

Aubrey® uses golden seaweed extract in their Age-Defying Moisturiser and SPF 15 Defense Moisturiser, because of its clinically proven effectiveness. In a study performed independently of Aubrey Organics, Inc.,

20 individuals tested Laminaria Ochroleuca extract in a test cream for 56 days to measure its anti-wrinkle properties. At the end of the study, 80% of the volunteers saw significant reduction in the appearance of wrinkle depth (see study below).

Laminaria Ochroleuca in Vivo Study   (Studied on Real Human Volunteers)

20 volunteers from age 35 to 55 applied a 2% concentration of Laminaria Ochroleuca extract in a test cream once a day for 56 days. After 56 days, their skin was evaluated in comparison to the first day of the study.
These were the results:
  • 80% of the volunteers had significant reduction in the appearance of wrinkle depth.
  • The Laminaria Ochroleuca extract also had significant effects on the hydration, firmness, and smoothness of the skin.

When purchasing any personal care product, it is very important to know the ingredients and to be informed about their safety and effectiveness. Delicate facial skin, in particular, may be very susceptible to the dryness and irritation that can be caused by harsh petrochemicals.

Aubrey Age Defying and SPF 15 Defense Moisturiser both contain naturally defensive elements that hydrate the skin and protect against the elements of nature, and both moisturisers contain only natural ingredients. Aubrey® uses only natural fragrances in their products, making them perfect for those with fragrance allergies or sensitivities.

*Permission to use study and photographs given to Aubrey Organics, Inc. May not be used or distributed without written consent of Biotech Marine.


Alaria Esculenta Extract   

Aubrey® has always been the leading manufacturer of natural skin care products. Although there are many petrochemical-laden anti-aging products on the market today, Aubrey® is committed to educating the public on healthy, natural alternatives. Alaria Esculenta, a type of nutrient-rich kelp, has many anti-aging and firming properties.

Alaria Esculenta grows mainly in the Northern Atlantic. It is known for its long, golden-brown fronds, and its unique ability to withstand harsh waves. It is found just beneath the surface of the water, and is known around the North Atlantic region for its nutritional value.

Alaria Esculenta Extract in Vivo Study

How effective is a 1% concentration of Alaria Esculenta extract in a test cream on "crow's feet" wrinkles?
Here's what the study reported:
  • 20 volunteers with an average age of 49.9 years used the Alaria Esculenta extract in a test cream for 28 days, applying it twice daily.

  • After 28 days, the researchers measured the volunteers' skin by cutometer, and found a 25% increase in firmness, and 20% increase in elasticity.

Whenever shopping for skin care, it is important to be educated on the ingredients of what you buy. Aubrey® is proud to use only natural ingredients. Moreover, Aubrey® skin care products are never tested on animals, as Aubrey® does not accept animal testing as proof of a product's safety or effectiveness when used by a human. Alaria Esculenta extract is a clinically proven, effective ingredient for use in in natural anti-aging products, and can be found in Aubrey®'s Revitalising Night Crème and Revitalizing Moisturiser.

*Permission to use study and photographs given to Aubrey Organics, Inc. May not be used or distributed without written consent of Biotech Marine.


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