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Clinical tests demonstrate topical application of carnosine (an amino acid) and vitamin E, two powerful antioxidants, plus milk thistle extract, a detoxifier, resulted in increased firmness and hydration, and advanced anti-wrinkle and anti-glycation activity on the skin. Glycation happens when sugar molecules bind to collagen and elastin proteins in the skin to form damaging free radicals (not unlike the free radicals caused by too much sun). Free radicals are a primary cause of aging. They lead to inflammation, which in turn breaks down the skin's connective tissue, resulting in wrinkles, yellowing of the skin, loss of elasticity due to a hardening of collagen and elastin fibres in the dermis, and other visible signs of aging. Studies conducted over 28 days show a synergistic blend of these three ingredients in a liposome delivery system helps stop glycation by preventing glucose/collagen bonds from forming and breaking down free radicals already present in the skin.Rejuvenating Properties of Carnosine, Milk Thistle & Vitamin E
This study involved 20 women ages 38 to 65. A test cream containing a liposome preparation of 2% carnosine, milk thistle and vitamin E was applied to the inner forearm of the subjects twice a day for 28 days.
Biomechanical properties of the skin were then evaluated by determining the skin's firmness, hydration and smoothness. Results showed this preparation improved all parameters in all subjects after 28 days of treatment when compared to untreated skin.
A test cream containing a liposome preparation of 2% carnosine, milk thistle and vitamin E was applied twice daily for 28 days to the crow's feet and foreheads of 20 women ages 38 to 65.
Wrinkle depth was evaluated after 14 days of treatment and again after 28 days. Results showed that at the 14 day mark, the depth of wrinkles was somewhat diminished. After 28 days of treatment, depth of wrinkles had been reduced by 27% in the crow's feet area, and by 24% on the forehead